Li-Huei Tsai

Professor Li-Huei Tsai is the Picower Professor of Neuroscience at the Department of Brain and Cognitive Sciences and an Investigator at the Picower Institute for Learning and Memory at MIT. Prof Tsai uses multi-omic approach to decipher the pathophysiology of Alzheimer’s dementia (AD). Her team pioneered the use of patient-derived induced pluripotent stem cells (iPSCs) to produce various brain cell types and a novel 3D brain tissue model of AD pathology. She also pioneered the use of non-invasive sensory stimulation to treat AD and other neurological disorders. Tsai is a Fellow of the American Association for the Advancement of Science, a Fellow of the National Academy of Inventors, a Member of the National Academy of Medicine, an Academician of the Academia Sinica in Taiwan, and a Member of the American Academy of Arts and Sciences. She is a recipient of the Mika Salpeter Lifetime Achievement Award, the 2018 Hans Wigzell Research Foundation Science Prize for her research on Alzheimer’s disease, and 2025 Distinguished Lecturer for Parkinson’s Disease Research, Diana Helis Henry and Adrienne Helis Malvin Medical Research Foundations. In 2022 she was named a Visiting Professor of the Vallee Foundation.